Aquamephyton

Generic Name: phytonadione (fye toe na DYE own)

Brand Names: Mephyton, Vitamin K1

What is Aquamephyton (phytonadione)?

Phytonadione is a man-made form of vitamin K. Phytonadione is important in the production of substances that cause the blood to clot.

Phytonadione is used to treat vitamin K deficiency and to treat certain bleeding or blood clotting problems.

Phytonadione may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Aquamephyton (phytonadione)?

Tell your doctor and dentist that you are taking phytonadione before having any type of surgery.

What should I discuss with my healthcare provider before taking Aquamephyton (phytonadione)?

Phytonadione may affect other medical conditions or treatments. Talk to your doctor before taking phytonadione if you have other health problems or conditions, or if you take other medications.

Phytonadione is in the FDA pregnancy category C. This means that it is not known whether phytonadione will be harmful to an unborn baby. Do not take phytonadione without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether phytonadione passes into breast milk and if it will affect a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take Aquamephyton (phytonadione)?

Take phytonadione exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each oral dose with a full glass of water.

Injectable forms of phytonadione are usually administered by a healthcare professional. If you are injecting phytonadione at home, your doctor or nurse will give you detailed instructions regarding preparation, administration, and storage of the medication.

Do not take more phytonadione than is prescribed.

It is important to take phytonadione regularly to get the most benefit.

Your doctor may want you to have blood tests or other medical evaluations during treatment with phytonadione to monitor progress and side effects.

Store phytonadione at room temperature away from moisture and heat. Protect phytonadione from light, as light decreases the effectiveness of the medication.

What happens if I miss a dose?

Contact your doctor if you miss a dose of this medication.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a phytonadione overdose are not known.

What should I avoid while taking Aquamephyton (phytonadione)?

Tell your doctor and dentist that you are taking phytonadione before having any type of surgery.

Aquamephyton (phytonadione) side effects

Seek emergency medical attention or contact your doctor immediately if you experience any serious side effects from phytonadione such as:

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  an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

  
  


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  dizziness;

  
  


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  fast or irregular heartbeats; or

  
  


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  increased sweating.

  
  

Other less serious side effects may be more likely to occur. Continue to use phytonadione and talk to your doctor if you experience

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  flushing of the face;

  
  


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  an unusual taste in the mouth; or

  
  


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  pain or irritation at the injection site (injectable form).

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Aquamephyton (phytonadione)?

Before taking phytonadione, tell your doctor about all other medicines you are taking, especially any of the following:

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  warfarin (Coumadin);

  
  


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  mineral oil;

  
  


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  orlistat (Xenical);

  
  


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  cholestyramine (Questran, Prevalite);

  
  


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  a salicylate such as aspirin (Acuprin, Ecotrin, Ascriptin, Bayer, others); choline salicylate and/or magnesium salicylate (Magan, Doan's, Bayer Select Backache Pain Formula, Mobidin, Arthropan, Trilisate, Tricosal), or salsalate (Disalcid);

  
  


• a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil, Nuprin, others), ketoprofen (Orudis, Orudis KT, Oruvail), naproxen (Naprosyn, Anaprox, Aleve), diclofenac (Voltaren, Cataflam), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketorolac (Toradol), sulindac (Clinoril), or tolmetin (Tolectin); or


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  an antibiotic.

  
  

You may not be able to take phytonadione, or you may require a dosage adjustment or special monitoring during treatment.

Medications other than those listed here may also interact with phytonadione. Tell your doctor about all other prescription and over-the-counter medicines that you take, including vitamins, minerals, and herbal products.

More Aquamephyton resources

• Aquamephyton Side Effects (in more detail)
• Aquamephyton Use in Pregnancy & Breastfeeding
• Aquamephyton Drug Interactions
• Aquamephyton Support Group
• 0 Reviews for Aquamephyton - Add your own review/rating

• Phytonadione Prescribing Information (FDA)


• Phytonadione Monograph (AHFS DI)


• Phytonadione MedFacts Consumer Leaflet (Wolters Kluwer)


• Mephyton Advanced Consumer (Micromedex) - Includes Dosage Information


• Mephyton Prescribing Information (FDA)


• Mephyton MedFacts Consumer Leaflet (Wolters Kluwer)


• Vitamin K1 Prescribing Information (FDA)

Compare Aquamephyton with other medications

• Hypoprothrombinemia, Anticoagulant Induced
• Hypoprothrombinemia, Not Associated with Anticoagulant Therapy
• Hypoprothrombinemia, Prophylaxis
• Vitamin K Deficiency

Where can I get more information?

• Your pharmacist has more information about phytonadione written for health professionals that you may read.

See also: Aquamephyton side effects (in more detail)