Tuesday, February 17, 2009

Dabigatran




In the US, Dabigatran (dabigatran systemic) is a member of the drug class thrombin inhibitors and is used to treat Prevention of Thromboembolism in Atrial Fibrillation.

US matches:

  • Dabigatran

  • Dabigatran Etexilate Mesylate

Scheme

Rec.INN

CAS registry number (Chemical Abstracts Service)

0211914-51-1

Chemical Formula

C25-H25-N7-O3

Molecular Weight

471

Therapeutic Category

Anticoagulant agent: Direct thrombin inhibitor

Chemical Names

N-[[2-[(p-amidinoanilino)methyl]-1-methyl-5-benzimidazolyl]carbonyl]-N-2-pyridiyl-ß-alanine (WHO)

3-{[(2-{[(4-Carbamimidoylphenyl)amino]-methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl](pyridin-2-yl)amino}propanoic acid (USAN)

ß-Alanine, N-[[2-[[[4-(aminoiminomethyl)phenyl]amino]-methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl- (USAN)

ß-Alanine, N-((2-(((4-((((hexyloxy)carbonyl)amino)iminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-, ethyl ester

Foreign Names

  • Dabigatranum (Latin)
  • Dabigatran (German)
  • Dabigatran (French)
  • Dabigatrán (Spanish)

Generic Names

  • Dabigatran (OS: USAN)
  • BIBR 953 ZW (IS)
  • UNII-I0VM4M70GC (IS)
  • Dabigatran Etexilate Mesilate (OS: USAN)
  • Dabigatran etexilate methanesulfonate (OS: JAN)

Brand Names

  • Pradaxa
    Boehringer Ingelheim, Australia


  • Pradax
    Boehringer Ingelheim, Canada


  • Pradaxa
    Boehringer Ingelheim, Germany; Boehringer Ingelheim, Denmark; Boehringer Ingelheim, Spain; Boehringer Ingelheim, United Kingdom; Boehringer Ingelheim, Croatia (Hrvatska); Boehringer Ingelheim, Ireland; Boehringer Ingelheim, Netherlands; Boehringer Ingelheim, Norway; Boehringer Ingelheim, Sweden; Boehringer Ingelheim International, Austria; Boehringer Ingelheim International, Luxembourg

International Drug Name Search

Glossary

ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

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